Table 40. Effects of various progestogens alone and with a known carcinogen on tumour incidence in rats
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چکیده
4.1 Absorption, distribution, metabolism and excretion The disposition of various formulations of oral contraceptives used in humans differs. In general, both the oestrogenic and progestogenic compounds in combined oral contraceptives are absorbed by the gut and metabolized largely in the liver. A fraction of the absorbed dose of ethinyloestradiol and several progestogens is excreted in the bile during IARC MONOGRAPHS VOLUME 72 220
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